Clinical evaluation of pregnant women with SARS-COV2 pneumonia: a real-life study from Egypt

Samy Zaky,Hossam Hosny,Hend Salah Abdelmenam,Mohamed Elnady,Shaimaa Soliman,Akram Abdelbary,Hala Zaid,Hamdy Ibrahim,Mohamed Hassany,Amin Abdel Baki,Noha Asem,Khaled Taema,Ahmad Said,Wagdy Amin,Sherief Abd-Elsalam,Ahmed S Mohamed,Gehan Elassal,Ehab Kamal

doi:10.1186/s42506-021-00092-z

Abstract

BackgroundKnowledge about the outcome of COVID-19 on pregnant women is so important. The published literature on the outcomes of pregnant women with COVID-19 is confusing. The aim of this study was to report our clinical experience about the effect of COVID-19 on pregnant women and to determine whether it was associated with increased mortality or an increase in the need for mechanical ventilation in this special category of patients.MethodsThis was a cohort study from some isolation hospitals of the Ministry of Health and Population, in eleven governorates, Egypt. The clinical data from the first 64 pregnant women with COVID-19 whose care was managed at some of the Egyptian hospitals from 14 March to 14 June 2020 as well as 114 non-pregnant women with COVID-19 was reviewed.ResultsThe two groups did not show any significant difference regarding the main outcomes of the disease. Two cases in each group needed mechanical ventilation (p 0.617). Three cases (4.7%) died among the pregnant women and two (1.8%) died among the non-pregnant women (p 0.352).ConclusionsThe main clinical outcomes of COVID-19 were not different between pregnant and non-pregnant women with COVID-19. Based on our findings, pregnancy did not exacerbate the course or mortality of COVID-19 pneumonia.

Highlights

The virus that causes Coronavirus infectious disease (COVID)-19 and the virus that caused the severe acute respiratory syndrome (SARS) outbreak in 2003 are genetically related to each other, but the diseases caused by them are completely different
The aim of this study is to clinically evaluate the effect of COVID-19 on pregnant women and to determine whether it was associated with increased mortality or need for mechanical ventilation in this special category of patients
We reviewed clinical data from the first 64 pregnant women with COVID-19 whose care was managed at these Egyptian hospitals from 14 March to 14 June 2020 as well as 114 non-pregnant women with COVID-19

Summary

Introduction

The virus that causes COVID-19 and the virus that caused the severe acute respiratory syndrome (SARS) outbreak in 2003 are genetically related to each other, but the diseases caused by them are completely different. COVID-19 is clinically milder than MERS or SARS in terms of severity and mortality This was a particular problem with early reports from China, and the authors rarely explained it. Most of the reports were of very small numbers; ; the larger studies reported few details. The aim of this study was to report our clinical experience about the effect of COVID-19 on pregnant women and to determine whether it was associated with increased mortality or an increase in the need for mechanical ventilation in this special category of patients

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Conclusion