Abstract
e16508 Background: Cervical cancer is the most common malignant tumor of the female reproductive system. Globally, there are an estimated 530,000 new cases of cervical cancer each year. One third of these cases occur in China, where the average age of cervical cancer patients is decreasing. To evaluate the efficacy of neoadjuvant chemotherapy (NACT) followed by radical surgery (RS) among patients with locally advanced cervical cancer (LACC) and survival outcomes. Methods: From January 2008 to December 2012, 800 previously untreated patients with LACC (stage IB2、IIA2 and part IIB, tumor diameter > 4 cm) from West China Second Hospital were assigned to receive either NACT followed by radical surgery (NACT- RS) or RS directly for clinical evaluation. Results: 36.63% of cervical cancer patients were under 40 years. The clinical response for NACT was 89.54%.Catheter removal time was shorter (29.84 days vs. 32.14 days, P < 0.05), percentage of operative complications (7.30% vs. 13.62%, P < 0.05) and radiochemot...
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