Abstract

The standard treatment in majority of the institutions is oral iron (OI), with blood transfusion reserved for severe or emergency cases. However, it is unreliable in the treatment of severe anemia. Blood transfusion has its own hazards, including transfusion of wrong blood and deadly infections like HIV, CMV, hepatitis and anaphylaxis. Thus, there is a need for a safe and effective alternative to OI or blood transfusion in the treatment of anemia. Iron dextran, the first parenteral iron used, lost its popularity due to anaphylaxis. Iron sucrose was then discovered as a parenteral iron that could be safe and effective. Hence based on above findings the present study was planned for Clinical Evaluation of Intravenous Iron Sucrose in Pregnant Anaemic Females.
 The present study was planned in Department of Obstetrics and Gynaecology, Madhubani Medical College and Hospital, Madhubani, Bihar. In the present study 50 females presenting in antenatal clinic with haemoglobin between 5-9 g% were enrolled in the present study. Iron sucrose (Injection Orofer S, Emcure Pharmacueticals Limited, India) was given in a dose of 200 mg intravenously twice weekly in 200 ml normal saline over a period of 15-20 min. First dose was given in the ward where equipment for cardiopulmonary resuscitation was available. The following doses were given on outpatient basis. Patients were observed for side effects or anaphylactic reactions. Any minor or major side effects were documented. All parameters were repeated at 2 wk interval till 8 wk.
 The data generated from the present study concludes that intravenous iron sucrose therapy was effective to treat moderate anaemia in pregnant women. Intramuscular preparations are known to be associated with local side-effects. Iron sucrose complex iv therapy was with negligible side effects. It caused rapid rise in haemoglobin level and the replacement of stores was faster.
 Keywords: Intravenous, Iron Sucrose, Pregnant, Anemic Females, etc.

Highlights

  • Anemia is a medical condition in which there is not enough healthy red blood cells to carry oxygen to the tissues in the body

  • The data generated from the present study concludes that intravenous iron sucrose therapy was effective to treat moderate anaemia in pregnant women

  • Iron sucrose complex iv therapy was with negligible side effects

Read more

Summary

Introduction

Anemia is a medical condition in which there is not enough healthy red blood cells to carry oxygen to the tissues in the body. When the tissues do not receive an adequate amount of oxygen, many organs and functions are affected. Anemia during pregnancy is especially a concern because it is associated with low birth weight, premature birth and maternal mortality. The body produces more blood to support the growth of your baby. If you're not getting enough iron or certain other nutrients, your body might not be able to produce the amount of red blood cells it needs to make this additional blood. It's normal to have mild anemia when you are pregnant. You may develop severe anemia from low iron or vitamin levels or from other reasons

Objectives
Methods
Results
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call