Clinical Evaluation of EMD (EMDOGAIN) Applied to Vertical Osseous Resorption in Periodontal Disease at Multi Clinics in Japan

Abstract

Objectives : The aim of the present study was to evaluate the effectiveness of EMDOGAIN® treatment through a multiple-clinic survey.Methods : The probing pocket depth (PPD), clinical attachment level (CAL,) and radiographic bone level (RBL) of 256 single-rooted teeth with partial vertical osseous defects in 185 clinics were evaluated at baseline and 8 months after surgical application of EMDOGAIN®. The number of walls, depth, and width of intrabony defects were measured.Results : At 8 months post-surgery, a PPD reduction of 3.58mm and a clinical attachment (CA) mean value of 2.87mm were obtained. The bone gain along the axis of the teeth determined in terms of RBL was on average 2.15mm. The deeper the PPD and bone defect depth, the greater the PPD reduction, the gain of CA, and the level of bone regeneration. The number of walls and defect width did not affect the post-surgery reduction of PPD, gain in CA or bone gain.Conclusion : The results of the present study showed no great difference with those obtained in studies performed in European and North American specialist clinics. The constant improvement regardless of number of walls or width of intrabony defects suggest that EMDOGAIN® should be indicated more widely than bone graft or GTR therapy.