Abstract
A higher beta(2)-microglobulin (beta(2)MG) removal rate is possible in dual-dialyzer hemodialysis (DDHD) because of the large internal filtration provided. In this treatment, in the first dialyzer, a large amount of water moves from the blood side to the dialysate side, and in the second dialyzer, it moves from the dialysate side to the blood side. Thus, both the direction of the water shift and the amount of water change within the dialyzer from the blood inlet port to the outlet port. A blood volume monitor was used to confirm that the internal filtration rate remains stable during the course of the dialysis treatment. The beta(2)MG removal rate and the weekly amount of solute removal by DDHD treatment was much higher than that for conventional HD.
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