Clinical evaluation of coronally advanced flap with or without platelet-rich fibrin for the treatment of multiple gingival recessions.

Abstract

The aim of this randomized, controlled study was to assess the clinical effect of platelet-rich fibrin (PRF) in combination with coronally advanced flap (CAF) on root coverage, esthetics, and patient satisfaction when compared to CAF alone for the treatment of multiple Miller class I recessions. A total of 24 patients with 52 Miller class I multiple recessions ≥3mm were included and divided into CAF + PRF and CAF groups. At baseline and 12months after surgery, recession height (RH), keratinized tissue height, gingival thickness (GT), and mean and complete defect coverage were evaluated. Patient satisfaction and root coverage esthetic scores were also assessed. Baseline RH in CAF + PRF and CAF groups was 3.15±0.24 and 3.36±0.34mm, respectively. Intragroup comparisons revealed significant differences at 12months for all parameters (p<0.05). RH reduction was 2.75±0.33 and 2.51±0.33mm (mean root coverage of 88.36 and 74.63%) in the CAF + PRF and CAF groups, respectively. Intergroup differences were found to be significant for GT gain (p<0.05). The additional use of PRF membrane did not provide additional benefits in terms of root coverage outcomes compared with CAF alone. The use of PRF membranes increased tissue thickness significantly.