Clinical evaluation of bioactive resin based pits & fissures sealants versus conventional resin based pits & fissures sealants in caries susceptible fissures in permanent molars: A randomized controlled

Abstract

Objectives: This study was carried out to evaluate the clinical performance of bioactive versus fluoride releasing resin-based pits and fissure sealants in molars in high caries risk patients regarding retention and caries incidence. Material and methods: A total of 38 participants received 38 pits and fissure sealants randomly using either; BioCoat™ by Premier® (Plymouth Meeting, Pennsylvania,USA) or Clinpro™ by 3M™ ESPE (St. Paul, Minnesota, USA) , all materials were utilized obeying manufacturers’ instructions. Sealants were evaluated using Simonsen’s criteria for retention and using VistaProof fluorescent camera for caries detection around sealants or in presealed fissures by two blinded assessors after 6-and 12- months. Chi square test was used to associate between the type of sealants and their clinical performance. Relative risk was used to assess the clinical significance. Survival rate was analysed using Kaplan-meier and Log-rank test Results: For retention, comparison between both sealants have shown no statistically significant difference throughout different follow up periods; baseline, 6 and 12 months (P = 1.0000, P = 0.9277 and P = 0.3185) respectively. There was 16% less risk for failure in retention for Biocoat sealant when compared to Clinpro sealant after 12 months (RR= 0.8366(95% CI 0.4306 to 1.6252; P =0.5985).