Abstract
In laparoscopy, the usual adhesion prevention techniques cannot be applied or are difficult to use. As a result, a viscoelastic gel was developed. Methods: In third party-blinded, randomized, four center studies, patients from 18-46 years underwent surgical laparoscopy in which adnexa and adjacent tissues were coated with viscoelastic gel. They underwent for a second look 6-10 weeks later. Adhesion scores of American fertility society were quantified with the blinded reviews of videotapes. Result: For 25 patients, surgery was done on 45 adnexa .Surgical sites with risk of adhesion was covered with approximately 15 ml of viscoelastic gel in approximately 90 seconds. For 24 control patients, surgery alone was done on 41 adnexa. Decrease in AFS score (11.9-9.1) was seen in treated adnexa. In control adnexa increase in AFS score (8.8-15.8) seen. The difference (42% reduction) seen in second look AFS score is significant (p < 0.01). Conclusion: Laparoscopic administration of viscoelastic gel was easy and had significant reduction in adnexal adhesions. The patients undergoing gynecological surgeries were benefited.
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