Clinical evaluation and assessment of the efficacy of platelet rich fibrin (PRF) on the stability of orthodontic implant

Abstract

The success of orthodontic treatment depends upon the anchorage. Mini-implants are widely been accepted as anchorage units, due to its size and convenience. However, implant failure is major concern. The placement of implant leads to micro-trauma leading to inflammation, and is found to be major reason of implant failure. Research to improve the stability of mini-implants are on rise. Platelet rich fibrin (PRF) is new generation platelet concentrate, which is found to increase the healing of tissues and hence used in trauma and surgeries. This study was undertaken to find whether PRF can enhance the stability of implant. This single blind split mouth study comprised of 16 subjects above 18 years of age. Group A (consisted of 16 implants which were coated before insertion) and group B (16 implants were normally inserted). The stability of the implant was recorded using resonance frequency analysis at insertion (T0), 24 hours (T1), 2 weeks (T2), at 4 weeks (T3), at 6 weeks and 8 weeks after insertion. Statistically significant findings were found when group A was compared to group B using ANOVA test (p<0.05). The stability of implant of group A (experimental group) at each time interval was greater than group B (control group). The stability of implants was found to be increased when they were coated with PRF than the normally inserted implant.