Abstract
The authors present the results of a prospective, open-label, post-registration comparative study of the monotherapy of mild to moderate acne with an inflammatory component. 30 subjects aged 15-35 were engaged in the study. Subjects from Group 1 (n = 15) received Clindovit® in the form of 1% gel, and subjects from Group 2 (n = 15) received a combination of erythromycin and zinc in the form of lotion. The duration of treatment and participation in the study was 8 weeks. Dynamics of clinical manifestations of the disease, Dermatology Life Quality Index (DLQI), Psychological and Social Effects of Acne (APSEA), frequency and severity of adverse events against the background of treatment were assessed. The results of the study enabled the investigators to make a conclusion about efficacy, safety and good tolerance of Clindovit® gel as a monotherapy of mild to moderate acne with an inflammatory component.
Highlights
Представлены результаты проспективного открытого пострегистрационного сравнительного исследования монотерапии акне легкой и средней степени тяжести с воспалительным компонентом
The authors present the results of a prospective, open-label, post-registration comparative study of the monotherapy of mild to moderate acne with an inflammatory component. 30 subjects aged 15—35 were engaged in the study
The results of the study enabled the investigators to make a conclusion about efficacy, safety and good tolerance of Clindovit® gel as a monotherapy of mild to moderate acne with an inflammatory component
Summary
Представлены результаты проспективного открытого пострегистрационного сравнительного исследования монотерапии акне легкой и средней степени тяжести с воспалительным компонентом. The results of the study enabled the investigators to make a conclusion about efficacy, safety and good tolerance of Clindovit® gel as a monotherapy of mild to moderate acne with an inflammatory component. В последние годы проведено много исследований, посвященных изучению эффективности наружной терапии акне с воспалительным компонентом препаратами клиндамицина фосфата. У 46 больных с акне умеренно-тяжелой степени, доказало эффективность клиндамицина [6].
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