Clinical efficacy ofMajoon FalasfaandRoghan-e-Surkhin post-stroke-disability: an open labeled, pre-post analysis

Abstract

AbstractObjectivesStroke is one of the leading causes of death and disability in India. The estimated adjusted prevalence rate of stroke range, 84–262/100,000 in rural and 334–424/100,000 in urban areas. A deficit in motor function affects mobility, daily activity of life. Rehabilitation is the most useful method to reduce deficit motor function. Hemiplegia (Falij),is one of the most common disability resulting from stroke has been described by Unani physicians, and they treat the disease effectively on the principle ofTanqia(evacuation) andTadeel(alterative). Hence, a study contemplated to determine the effectiveness ofMajoon Falasfa(MF)and Roghan-e-Surkh(RS) in post-stroke disability.MethodsThis trail was an open labeled, pre-post analysis, carried out at the National Institute of Unani Medicine (NIUM), on thirty (n=30) subjects of both genders, with post-stroke disability, and given MF 6 g orally with water in the morning and evening on empty stomach daily along with massage of 15 mL RS on the affected part once a day for 45 days with three follow up fortnightly (i.e. 15th, 30th, and 45th day). Patients were assessed on each follow up based on Barthel Index of Activities of Daily Living (ADL). Pre- and post-treatment values of the scale were analyzed statistically using Student’s ‘t’ test and paired Proportion test.ResultsThe treatment difference as pre-post values determine with Barthel Index was found statistically highly significant (p<0.001). Safety parameters found within the normal range.ConclusionsFinding of this trial recommended that both Unani formulations are effective in the management of post-stroke disability, and it can be used to decrease the dependency and boost the quality of life of the patients. No adverse effect was noted during the treatment of test formulations.