Clinical Efficacy of Dienogest Combined with Wenjing Tang in Adenomyosis

Abstract

Objective: To investigate the clinical efficacy of Dienogest (DNG) combined with Wenjing Tang Formula in patients with uterine adenomyosis. Methods: 60 patients with adenomyosis were randomly divided into Group A and Group B. Group A patients received continuous oral treatment with DNG 2 mg/d for 3 months, while Group B patients were given Wenjing Tang Formula based on Group A treatment. The treatment effect, size of adenomyoma and incidence of adverse reactions were compared between the two groups. Results: The total effective rate of treatment in Group B was 96.67%, which was significantly higher than 73.33% in Group A (P < 0.05); the size of uterine adenomyoma in Group B was significantly smaller than that in Group A, with a significant difference (P < 0.05). In terms of the incidence of adverse reactions, group B was 6.67%, which was significantly lower than 26.67% in group A (P < 0.05). Conclusion: The treatment of adenomyosis of the uterus via dienogest combined with the addition and subtraction of Wenjing Tang showed higher therapeutic efficacy and significant tumor shrinkage, and at the same time, it could reduce the incidence of adverse reactions, which has a good prospect of clinical application, and it is recommended to be promoted for use in clinical practice.