Clinical efficacy of comprehensive hyperbaric oxygen in treatment of the patients with sudden hearing loss

Abstract

Objective To investigate the clinical efficacy of comprehensive hyperbaric oxygen (HBO) in the treatment of the patients with sudden hearing loss. Methods Totally, 80 patients with sudden hearing loss who were admitted into our hospital for treatment from June 2015 to March 2017 were selected as research subjects, and were divided into the observation group (n=40) and the control group (n=40), in accordance with the sequence of admission. The control group was given volume expansion to improve hemorheology, vasodilator to improve microcirculation, glucocorticoids, neurotrophic drugs and ginkgo biloba extract dripping pills, while the observation group received HBO in addition to the treatment received by the control group. One course of treatment for all patients in the 2 groups was 10 days, and following 3 courses of treatment, changes in hearing and clinical efficacy before and after treatment for the patients of the 2 groups were compared between the 2 groups. Results Following treatment for 3 courses for the observation group, 4 cases were cured, 21 cases were markedly effective, 10 cases were effective and 5 cases were ineffective, with a total effective rate of 87.5%, while for the control group, no cases were cured, 5 cases were markedly effective, 22 cases were effective and 13 cases were ineffective, with a total effective rate of 67.5%. Statistical significance could be seen, when comparisons were made between the observation group and the control group (P 0.05). After 2 courses of treatment, the value of low frequency hearing for the observation group increased more significantly, as compared with that of the control group[(37.39±5.77) vs (23.91±4.08) dB, P 0.05). After 3 courses of treatment, the increased values of both low frequency and high frequency hearing for the patients of the observation group were all significantly better than those of the control group [low frequency: (45.99±5.98) vs (36.79±5.72) dB; high frequency: (19.63±3.94) vs (9.70±2.17)dB, P<0.05]. Conclusions Comprehensive HBO treatment could effectively improve the hearing level of the patients with full frequency sudden hearing loss, which was worth further clinical popularization. Key words: Hyperbaric oxygen treatment; Sudden hearing loss; Full frequency hearing loss; Therapeutic effect