Clinical Efficacy of Amroid Tablet and Amroid Ointment in the Management of Arsha (Hemorrhoids) - A Single-Arm Open-Label Clinical Trial

Abstract

Arsha is very common anorectal disease presents with bleeding per rectum, pain in ano, peri anal inflammation, and itching per ano. In modern system, hemorrhoids is defined as abnormal engorgement of vascular anal cushions. Incidence of hemorrhoids increases day-by-day due to poor food habits and lifestyle. There are many medical and surgical methods available for hemorrhoids but now-a-days demand of Ayurvedic herbal preparation is increasing in the society. An open labeled single arm prospective trail were conduct to evaluate the efficacy of Amroid tablet and ointment in cases of Arsha, that is, hemorrhoids. Total 144 patients of 1st, 2nd, 3rd degree hemorrhoids were treated with two tablets of Amroid orally thrice a day and Amroid ointment applied locally at per rectal before and after defecation for 4 weeks and patients were follow for 8 weeks. Highly significant (P < 0.0001) results were found in Ano-rectal pain, inflammation, bleeding per ano, itching per ano, constipation, prolapsed of piles even after treatment of 1 week, and it sustained throughout follow-up of 8 weeks. This clinical trial concluded that Amroid tablet and Amroid ointment have been potential to cure hemorrhoid up to third degree.