Abstract
Objective To investigate the clinical efficacy and safety of fengliaochangweikang capsule combined with mesalazine on patients with recurrent ulcerative colitis.Methods Fifty-seven cases of chronic recurrent ulcerative colitis from March 2008 to March 2012 in people' s hospital of Yuanping were divided into treatment group and control group.Patients in the control group were given oral mesalazine,patients in treatment group were given fengliaochangweikang capsule combined with mesalazine.The clinical efficacy,clinical symptoms,endoscopy,histological examination results and adverse reactions of both groups were observed.Results Clinical symptoms and the clinical effect of treatment group,remission,endoscopy,histological examination results were significantly superior to those in the control group(P ＜ 0.05).The total incidence of adverse reaction was 32.26％ in treatment group and it is significantly lower than that in control group (53.85％),the difference was statistically significant (x2 =9.506,P ＜ 0.05).Conclusions Fengliaochangweikang capsule combined with mesalazine in treatment of chronic recurrent type of ulcerative colitis is better than single mesalazine,and the security is high,so it is worthy of clinical application. Key words: Fengliaochangweikang capsule ; Mesalazine ; Ulcerative colitis ; Clinical effect
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