Abstract
Summary1. Therapeutic effects of lithium carbon ate were studied on a total of 55 cases comprising 15 cases of involutional melancholia, 23 cases of monopolar depression and 17 of bipolar depression.2. Lithium carbonate was found to be effective to seven cases (47%) of involutional melancholia, 14 cases (61%) of monopolar depression, and nine cases (53%) of bipolar depression, indicating no significant difference among these three groups.3. There was observed no correlation between the characteristics of symptoms and the therapeutic effect in depressive states.4. The serum lithium concetration in the lithium responder was 0.47±0.13 mEq/1 and that in non‐responder 0.55 ±0.14 mEq/1, showing no significant difference between the two groups.5. Lithium carbonate has been found to be effective in the treatment of depressive states. Therefore, it requires further studies using the double‐blind controlled method for clarification of its therapeutic effects.
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