Abstract
Objective This study was aimed to investigate the clinical effect of Chinese herbal decoction combined with basic chemoradiotherapy and nursing intervention in the treatment of cervical cancer and the effect on serum carbohydrate antigen 125 (CA125), carcinoembryonic antigen (CEA), and tumor necrosis factor-α (TNF-α) levels. Methods A total of 200 cervical cancer patients in our hospital from June 2015 to November 2018 were selected and randomly divided into a study group and a control group. The control group was given chemoradiotherapy and psychological nursing treatment, and the study group was given self-made Chinese herbal decoction on the basis of the control group. The clinical efficacy and serum CEA, CA125, and TNF-α levels were assessed. Results After treatment, the total effective rate of the study group was significantly higher than that of the control group. The levels of serum CEA, CA125, and TNF-α were decreased in the two groups after treatment, and the decrease in the study group was more significant than that in the control group. After treatment, CD3+ and CD4+ levels were increased compared with those before treatment, and the increase in the study group was also more obvious than that of the control group. The level of CD8+ was decreased compared with before treatment, and the decrease in the study group was more notable than that of the control group. The two-year cumulative survival rate of the study group was markedly higher than that of the control group. The quality-of-life of patients treated for 3 months, 1 year, and 2 years was dramatically improved compared to before treatment. The incidence of adverse reactions in the study group was lower than that of the control group. Conclusion The treatment of basic chemoradiotherapy and psychological nursing intervention combined with Chinese herbal decoction on cervical cancer patients can improve the clinical treatment effects, improve the patient's body immunity, reduce serum CEA, CA125, and TNF-α levels, prolong survival time, improve life quality, and reduce the incidence of adverse reactions, and it is worthy of clinical promotion.
Highlights
Cervical cancer, which originates in the cervix of women, is a common clinical gynecological malignant tumor and currently accounts for the second highest incidence of gynecological malignancies [1]
The wide variety of traditional Chinese medicine (TCM) and the different compatibility methods make the current analysis of the cervical cancer prescriptions limited to the summary of the experience of famous doctors [10]. erefore, this study explores the clinical effects of Chinese herbal decoction combined with basic chemoradiotherapy and nursing intervention on cervical cancer and the effects on carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), and tumor necrosis factor-α (TNF-α) levels. e report is as follows
There was no significant difference in the levels of serum CEA, CA125, and TNF-α between the two groups of patients. e levels of serum CEA, CA125, and TNF-α were decreased after treatment in the two groups, and the study group decreased more significantly than the control group (P < 0.05) (Figures 1–3 )
Summary
Cervical cancer, which originates in the cervix of women, is a common clinical gynecological malignant tumor and currently accounts for the second highest incidence of gynecological malignancies [1]. Rogers et al pointed out that chemoradiotherapy can be used to treat cervical cancer, which can kill tumor cells better and prolong the survival time of patients [7]. Li et al suggested that the combination of Chinese herbal decoctions and conventional treatment can effectively improve the immune function of patients, thereby reducing the toxic side effects of the treatment on patients [8]. With the development of the traditional Chinese medicine (TCM) industry in China, TCM has a unique advantage in treating cervical cancer and other gynecological tumors because of its characteristic of syndrome differentiation and rich experience in gynecological treatment [9]. Erefore, this study explores the clinical effects of Chinese herbal decoction combined with basic chemoradiotherapy and nursing intervention on cervical cancer and the effects on CEA, CA125, and TNF-α levels. The wide variety of TCM and the different compatibility methods make the current analysis of the cervical cancer prescriptions limited to the summary of the experience of famous doctors [10]. erefore, this study explores the clinical effects of Chinese herbal decoction combined with basic chemoradiotherapy and nursing intervention on cervical cancer and the effects on CEA, CA125, and TNF-α levels. e report is as follows
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