CLINICAL EFFECTS OF ASTHMA AND BRONCHIECTASIS COEXISTENCE

Abstract

SESSION TITLE: Allergy and Airway SESSION TYPE: Original Investigation Posters PRESENTED ON: 10/10/2018 01:00 PM - 02:00 PM PURPOSE: Both asthma and bronchiectasis are important community health problems. In many patients, asthma and bronchiectasis coexist, and bronchiectasis has been shown to worsen asthma control with pulmonary complications. The aim of this study is to evaluate the clinical effects of asthma and bronchiectasis coexistence. METHODS: In this study, patients admitted to the Pulmonology Department of Akdeniz University Medical Faculty between January 1, 2014 and January 1, 2017 were evaluated. The patients were divided into three groups, asthmatics, bronchiectasis and asthma+bronchiectasis. The diagnosis of asthma was made according to the Global Initiative For Asthma (GINA) guidelines. The diagnosis of bronchiectasis was confirmed by high resolution computerized tomography. Sociodemographic data, comorbidities, physical examination findings, respiratory function test results were recorded in the data on the whole of the cases. Patients with asthma-COPD overlap syndrome, patients with cystic fibrosis were excluded from the study. RESULTS: One hundred-twenty seven patients with mean age of 44.8 years were included in the study. Fifty-six of them were male and 71 were female. 53 (41.7%) of these patients were asthmatics, 53 (41.7%) were bronchiectasis, and 21 (16.5%) were asthmatics+bronchiectasis. When all three groups were compared FEV1 (%), FVC (%), FEV1/FVC (%) and FEV1 (L) values were significantly lower in patients with asthma + bronchiectasis group (p=0.000). According to the GINA guidelines, asthma control levels were significantly worse in patients with asthma and bronchiectasis. When all three groups compared there was no statistically significant difference between the numbers of hospitalization (p=0.21) and exacerbations (p= 0.056). The most frequent symptom was dyspnea in asthma+bronchiectasis group, whereas the most frequent symptom was sputum in bronchiectasis group. CONCLUSIONS: In our study, asthmatic patients with bronchiectasis showed lower respiratory function test results and worse asthma control levels than other groups, but hospitalization and exacerbations rates were similar in all groups. CLINICAL IMPLICATIONS: Asthmatic patients with bronchiectasis showed lower respiratory function test results and worse asthma control levels. This group of patients should be evaluated more carefully. DISCLOSURES: No relevant relationships by Zehra Boztepe, source=Web Response No relevant relationships by Aykut Cilli, source=Web Response No relevant relationships by fatih uzer, source=Web Response