Clinical Effectiveness of the Du Pont acaMeasurement of Creatine Cinase MB in Serum from Patients in a Coronary-Care Unit

Abstract

Abstract Vol. 30 p 1553, Insert the symbol "○" in the sublegend to Fig. 1, third line, to read "...method: ○, activity..." Vol. 31 p 572, middle of right column: delete the three repeated lines of type. p 575, in "Table 1 (continued)," the first column heading hould read "Sample size, ND = ND·" p 616, left column, first text paragraph: the second sentence should read, "This nonlinear protein binding explains the dependence of renal clearance of disopyramide on total disopyramide concentration in serum and the lack of dependence of renal clearance on the concentration of free disopyramide (5). Furthermore, the pharmacological response to this drug is better correlated with the concentration of the free drug in serum than with its total concentration (4, 6); we thus condude that both the free fraction and the total concentration should be measured when one is monitoring arrhythmic patients who are being treated with his drug." p 617, left column: delete the two lines of text following the first paragraph of Results, and delete the three lines following the second paragraph. p 640: Three lines are missing in the section on Ferritin standards, as follows: "Ferritin from human liver, 9.7 µg per bottle, i.e., 9.1 mg/L (National Institute for Biological Standards and Controls, Hampstead-Holly Hill, London, reference 80/602)." p 641, left column, third line of text at bottom: "3988" should read "398.8" and "4140" should read "414.0." p 647, middle column, preceding the 10th line from bottom, insert: "Using this method, we found the ... " p 655, right column: the concluding paragraph (preceding the references) should read as follows: "Our results indicate that assay of serum SHBG is of value in the analysis of risk factors for mortality in post-menopausal women. Whether low SHBG concentration in these women primarily reflects androgen excess, estrogen deficiency, or other endocrine or metabolic changes remains a subject for further study, as does the relationship to adipose tissue distribution."