Clinical effect of percutaneous vertebroplasty for severe osteoporotic vertebral body compression fractures combined with intraosseous vacuum phenomena

Abstract

Objective: To investigate the clinical efficacy of percutaneous vertebroplasty (PVP) in the treatment of severely compressed bone fractures with intraosseous vacuum phenomena. Methods: From September 2006 to December 2017, 25 cases of severe compression fracture combined with intraosseous vacuum phenomena received PVP treatment. The clinical data of these patients were retrospectively analyzed. The success rate of PVP procedure was analyzed, and regular follow-up was conducted after the operation. Pain relief rate was recorded. Results: All patients received PVP operation under local anesthesia, and two patients received repeat PVP 3 d later due to poor pain relief effect. Postoperative pain assessment was followed up for 24 h, 1 week, 1, 3, 6 and 12 months, and the effective rates were recorded. The effective rates were 72% (18/25) , 64% (16/25) , 68% (17/25) , 76% (19/25) , 76% (19/25) and 70.8% (17/24) , respectively. Chi-square test showed no significant difference in pain symptoms at each time point (χ2=1.326, P>0.05) . Conclusions: PVP is a safe and effective treatment for severe bone vertebral compression fractures with intraosseous vacuum phenomena. Key words: Percutaneous vertebroplasty; Vertebral compression fracture; Severity; Vacuum phenomena; Osteoporosis