Clinical effect of integrated TCM and western medical treatment on patients with diabetes 2 with cerebral infarction with yin deficiency and blood stagnation theory

Abstract

Objective To investigate the advantages of integrated treatment of both Traditional Chinese Medicine (TCM) and alpha-lipoic acid on patients with diabetes 2 with cerebral infarction with yin deficiency and blood stagnation. Methods A total of 202 patients with diabetes 2 with cerebral infarction with yin deficiency and blood stagnation were randomly divided into two groups, with 101 cases in each group. All patients were treated by routine treatment. The patients in the control group were treated with α-alpha sulfur acid, and the patients in the treatment group were given the self-made TCM decoction. Before and after treatment, the superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), malondialdehyde (MDA), blood glucose, blood lipid, beta cell function index were detected. The patients were measured by National Institutes of Health Stroke Scale (NIHSS). The clinical effect was evaluated by calculating the patient efficacy index according to TCM syndrome integral. Results SOD and GSH-Px significantly increased in the treatment group after treatment, MDA decreased significantly. Compared with the control group, NIHSS, blood glucose, blood lipid, HOMA-IA significantly decreased in the treatment group. Conclusions Integrated treatment of Traditional Chinese Medicine and alpha-lipoic acid for patients with diabetes 2 with cerebral infarction with yin deficiency and blood stagnation theory, can significantly reduce the oxidative stress, decrease blood glucose andblood lipid, obtain good curative effect and less adverse reactions. The treatment is worthy of clinical promotion. Key words: Traditional Chinese and Western medicine treatment; Cerebral infarction; Type 2 diabetes; Oxidative stress; Clinical effect