Clinical effect of facial contour remodeling by using transplantation of the autologous granular fat grafting combined with botulinum toxin A injection

Abstract

Objective To discuss the clinical effect of facial contour remodeling using transplantation of the autologous granular fat grafting combined with botulinum toxin A injection. Methods Negative-pressure liposuction was carried out in the inner thigh or abdomen using liposuction needle connected with an injector, to let stand for layered, discharge lower layer water, rinse, extract the fat particles into a 2 ml syringe, inject into facial depression area with multipoint, multiple-tunnel, and multilayer manner, over injection of about 20%-30% every time. 89 patients received the injection; some accepted two injections; 13 cases were injected in temple (14.6%), and 16 in forehead (17.98%). 30 of them received subcutaneous injection of botulinum toxin A, each side dose was less than 20 U. Results Patients had been followed up for 3-36 months, and obvious improvements were observed in facial contour in the frontal and temporal region as well as the skin texture; the survival rate of fat granule reached to 60%-80%. No hematoma, nodes and infection been observed. Patients combined with botulinum toxin A injection had more ideal facial contour and more satisfaction. Conclusions Autologous fat granules transplantation in the face has stable clinical effect, and combining with botulinum toxin A injection can improve facial contour. It is a safe, ideal treatment in facial rejuvenation and facial contour remodeling and it therefore can be widely recommended in clinical treatment. Key words: Autologous fat grafting; Fat granule; Botulinum toxin A; Contour remodeling