Clinical Diagnosis of White Matter Softening in Premature Infants Based on Electroencephalogram (EEG).

Abstract

Periventricular white matter softening in preterm infants can lead to severe sequelae and greatly affects the quality of life of preterm infants, and early diagnosis is of great clinical significance and value. The purpose of this study is to select a diagnostic test scientifically and rationally, to interpret and evaluate the results of the diagnostic test, and to evaluate the selected diagnostic method. Although DWI is a sensitive method for early diagnosis of PVL, it is not suitable for critical preterm infants. Therefore, according to clinical research data and the basic hardware conditions of our hospital, video EEG was chosen as the target diagnostic test method to explore whether VEEG can be used for early diagnosis of PVL. According to the results of this study, video EEG may play an important role in the early diagnosis of PVL, and it is believed that video EEG can be used as an auxiliary examination tool, especially for some critical preterm infants who are not suitable for DWI examination, and it can be used as an electrophysiological examination index for the preliminary diagnosis of periventricular white matter softening in preterm infants to indicate that the clinic should carry out necessary and appropriate diagnostic tests. The timely intervention and the results of VEEG are valuable for the assessment of the prognosis of critically ill preterm infants as raw data. However, the use of VEEG to screen clinically suspicious PVL preterm infants is a new attempt, and although good results have been achieved in foreign countries, this study has been conducted only recently in China and requires further exploration.