Abstract
We defined the positive predictive accuracy of a hospital-based clinical diagnosis of leptospirosis in 9 provinces across Thailand. Of 700 suspected cases, 143 (20%) were confirmed by laboratory testing. Accuracy of clinical diagnosis varied from 0% to 50% between the provinces and was highest during the rainy season. Most confirmed cases occurred in the north and northeast regions of the country.
Highlights
We defined the positive predictive accuracy of a hospital-based clinical diagnosis of leptospirosis in 9 provinces across Thailand
A 5-mL serum sample was taken to be cultured for Leptospira, another 5-mL serum sample was taken for serologic testing, and a third sample was taken 2 weeks later for serologic testing
Of the 700 patients who received a clinical diagnosis of leptospirosis, 143 (20%) received a confirmed diagnosis of leptospirosis based on Leptospira isolation, Microscopic agglutination test (MAT) testing, or both (Table)
Summary
We defined the positive predictive accuracy of a hospital-based clinical diagnosis of leptospirosis in 9 provinces across Thailand. Before 1996, the number of cases reported to the Thailand Department of Disease Control (DDC) was ≈200 per year. Most cases (90%) throughout this period were reported in northeast Thailand.
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