Clinical correlation of pretibial myxedema with malignant exophthalmos.

Abstract

Article1 May 1954CLINICAL CORRELATION OF PRETIBIAL MYXEDEMA WITH MALIGNANT EXOPHTHALMOSWILLIAM H. BEIERWALTES, M.D., F.A.C.P.WILLIAM H. BEIERWALTES, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-5-968 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlmost 100 patients with localized pretibial myxedema had been reported by 1949.1The association of these lesions with exophthalmic goiter has been noted as early as 1930.2Curtis, Cawley and Johnwick3in 1949 reported the association of malignant exophthalmos and pretibial myxedema in three cases studied by them and in seven others known or reported previously. These authors also first emphasized3that both the malignant exophthalmos and the localized myxedema might be due to the same factor, i.e., a local effect of thyroid-stimulating hormone, T.S.H., in the extraocular tissues and in the subcutaneous areas of the anterior lower leg. Review...Bibliography1. French GN: Localized pretibial myxedema, New England J. Med. 241: 299, 1949. CrossrefMedlineGoogle Scholar2. O'Leary PA: Localized solid edema of the extremities in association with exophgoiter, Arch. Dermat. and Syph. 21: 57, 1930. CrossrefGoogle Scholar3. CurtisCawleyJohnwick ACEPEB: Association of progressive (malignant) exophthalmos and localized myxedema, Arch. Dermat. and Syph. 60: 318, 1949. CrossrefGoogle Scholar4. Beierwaltes WH: Irradiation of the pituitary in the treatment of malignant exophthalmos, J. Clin. Endocrinol. 11: 512, 1951. CrossrefGoogle Scholar5. Beierwaltes WH: X-ray treatment of malignant exophthalmos: a report on 28 patients, J. Clin. Endocrinol. and Metabolism 13: 1090, 1953. CrossrefGoogle Scholar6. ThompsonMeans WOJH: A comparison of exophthalmic goiter in Boston and Chicago, with special reference to iodine reaction, J. A. M. A. 99: 1483, 1932. CrossrefGoogle Scholar7. Mulyaney JH: Exophthalmos of hyperthyroidism: differentiation in mechanism, pathology, symptomatology, and treatment of two varieties, Am. J. Ophth. 27: 589 (June); 693 (July); 820 (August), 1944. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Received for publication November 20, 1953.From the Department of Internal Medicine, University of Michigan Medical School, and University Hospital, Ann Arbor. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThyroid dermopathy—a diagnostic clue of hidden hyperthyroidismLocalized Myxedema of the Foot: A Rare Presentation of Graves' DermopathyHypothyroid Graves’ disease complicated with elephantiasis nostras verrucosa (ENV): a case report and review of the literatureOrbital decompression in Graves’ ophthalmopathy associated with pretibial myxedemaEndocrine-skin interactionsThe cutaneous mucinosesHyperthyroidism. Causes, etiology of Graves’ disease, clinical features, general aspects of treatmentThe Nature and Significance of the Long-Acting Thyroid StimulatorLiteraturLokalisiertes Myxödem bei HypothyreoseLocalized (Pretibial) MyxedemaChronic Pseudotumoral Edema of the Conjunctiva*Circumscriptes Myxoedem und endocriner ExophthalmusLOCALIZED PRETIBIAL MYXEDEMA: REPORT OF TWO CASES TREATED WITH HYDROCORTISONE BY LOCAL INJECTION*RICHARD W. DYKE, M.D., F.A.C.P., CLAYTON E. WOOD, M.D., SOPHOCLES D. MARTY, M.D.Endokrine Gesichtspunkte der exophthalmischen Ophthalmopathie 1 May 1954Volume 40, Issue 5Page: 968-984KeywordsEdemaHospital medicineLesionsMusclesParalysisThyroidThyroid-stimulating hormoneUlcers Issue Published: 1 May 1954 PDF downloadLoading ...