Abstract
BackgroundThe aim of this study is to explore the different kinds of endolymphatic hydrops and the sensitivity of vestibular evoked myogenic potentials (VEMP) and electrocochleography in their diagnosis. Three groups of patients were selected according to the diagnosis, definitive MD (DMD), cochlear MD (CMD), and recurrent vestibulopathy (RV) groups. A basic audiological evaluation was carried out. It included pure tone audiometry, speech audiometry, acoustic immittancemetry testing and electrocochleography, cervical VEMP (c-VEMP), and ocular VEMP (o-VEMP).ResultsThe overall sample was 40 cases, 13 with DMD, 10 with CMD, and 17 with RV. The mean age is variable between groups (p-value < 0.001) with the highest in the DMD group (38.3 ± 7.4 years) and the lowest in the CMD group (25.2 ± 4.6 years). The male to female ratio is variable between groups of the study (p-value = 0.03) with the highest ratio 9:4 in the DMD group. There was a significant difference between groups (p < 0.001) regarding dizziness. Asymmetric response of c-VEMP was seen in nine (69.2%) of DMD cases, in 14 (82.4%) of RV cases, and only in three (30%) of CMD cases (p-value < 0.001). Low amplitude of o-VEMP was seen in 11 (84.6%) of DMD cases, 9 (90%) of CMD cases, 15 (88.2%) of RV cases, and only two (25%) of normal cases (p-value = 0.002). A significant difference was found between definitive and cochlear Meniere’s as regards o-VEMP inter-aural amplitude difference (IAD) (p-value = 0.032) only. There was a significant positive strong correlation between age and EcochG SP/AP ratio left ear, o-VEMP IAD, and o-VEMP left ear n1. In addition, there is a significant positive weak correlation between duration and EcochG SP/AP ratio left ear and c-VEMP left ear n1.ConclusionsAsymmetric response of c-VEMP can be used as a diagnostic tool to differentiate different kinds of MD: DMD, RV, and CMD.
Highlights
The aim of this study is to explore the different kinds of endolymphatic hydrops and the sensitivity of vestibular evoked myogenic potentials (VEMP) and electrocochleography in their diagnosis
The patients were divided into three groups and were selected according to the diagnosis: group 1: patients with definitive Meniere’s disease (MD) (DMD), group 2: patients with recurrent vestibulopathy (RV), and group 3: patients with cochlear MD (CMD)
Seventeen patients with recurrent vestibulopathy: Those were a group of patients with a history of more than a single episode of vertigo, and the duration of the vertigo was characteristic of that occurring with hydrops, but without auditory or neurological symptoms or signs
Summary
The aim of this study is to explore the different kinds of endolymphatic hydrops and the sensitivity of vestibular evoked myogenic potentials (VEMP) and electrocochleography in their diagnosis. Meniere’s disease (MD), one of the most common disorders of the inner ear, is thought to be an idiopathic progressive disease. It is caused by hair cell degeneration in the cochlea and vestibule. The excess hydraulic pressure within the inner ear’s endolymphatic system causes unstable hearing loss, occasional vertigo, tinnitus or ringing in the ears, and aural fullness. The term endolymphatic hydrops can be synonymously used with MD and Ménière’s syndrome [3]. Definitive Meniere is diagnosed by the following criteria: two or more episodes of vertigo that lasted at least 20 min in addition to audiometrically documented hearing
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
