Abstract
Introduction: Clinical dentistry and primary oral care continue to experience significant improvements in quality at different levels of dentistry. These changes and improvements are of great benefit to both patients and clinicians because of significant achievements and advances in the physical, chemical, and biological sciences. Nanotechnology and its varied products are eloquent examples of these revolutionary trajectories in scientific discoveries and endeavors. Scientific revolution of nanotechnology has afforded the dental profession with a wealth of novel nanobiomaterials, templates for dental tissues regeneration, oral fluid nanodiagnostics, and the potential ability to use nanoparticles to replace lost dental hard tissues. Materials and Methods: A manual and systematic electronic search was conducted using the PubMed database. Several keywords were used: “nanocharacterization” “nanoclinical applications” “endodontics” “nanodentistry” “nanotechnology (263) (278) papers were excluded because they were duplicated papers,” “nanoparticles” and “regeneration.” Relevant articles published up to 2016 in the English language were retrieved. Results: Initial electronic and manual searches identified (571) studies. Preliminary analysis was performed on a total of (332) publication by screening titles and abstracts of articles. A second phase, data studies, or unrelated reports were excluded. Full texts of the remaining (54) papers were retrieved. A manual search added (6) publications on the topic to give a total of (60) publications, literature reviews, which were included in this review. Conclusions: Physical and chemical improvements in nanotechnology products continue to occur and may soon lead to the development of “smart” endodontic therapeutic agents and materials. The future looks auspicious for sustained dramatic inventions in novel nanomaterials for clinical dental applications.
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