Clinical characters and survival outcomes in primary squamous cell carcinoma of the retromolar trigone

Abstract

BackgroundsTo better study the clinical characters and survival outcomes associated with primary squamous cell carcinoma of the retromolar trigone (primary SCC RMT), this study was analyzed through the SEER database to determine the factors. MethodThe SEER database was searched for patients with primary SCC RMT between 2000 and 2018. Data on age, sex, race, marital status, radiotherapy, chemotherapy, etc. of the patients were collected and analyzed. R software was used to create prognostic nomograms to forecast Cancer-specific survival likelihood. The consistency index, calibration curve, and receiver operating characters curve evaluated the prediction abilities of the nomogram. Result3128 cases of primary SCC RMT were screened. Patients were randomly divided into 465 and 208 on a 7:3 basis. Univariate Cox regression showed that age, marital status, radiotherapy, chemotherapy, surgery, lymph node surgery, T-stage, N-stage, and M-stage were primary SCC RMT correlates, and multivariate Cox regression revealed that age, Surgery, T-stage, and N-stage were independent risk factors for primary SCC RMT. In addition, calibration curves showed good agreement between nomogram predictions and actual 1-, 3-, and 5-year CSS incidence in both the primary and the validation cohorts. ConclusionsBy analyzing the SEER database, we constructed a nomogram of the factors associated with primary SCC RMT and a corresponding validated analytical model, in the hope that it can better help guide clinical treatment.