Clinical Characteristics of Newborns Born to Mothers with COVID-19.

Katarzyna Wróblewska-Seniuk,Izabela Miechowicz,Agnieszka Basiukajć,Jan Mazela,Dobrochna Wojciechowska,Mayanthi Telge

doi:10.3390/jcm10194383

Katarzyna Wróblewska-Seniuk, Izabela Miechowicz + Show 4 more

Open Access

https://doi.org/10.3390/jcm10194383

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Abstract

(1) Background: According to the literature, most outcomes of neonates born to mothers infected with SARS-CoV-2 are favorable. This study aimed to assess the clinical characteristics of newborns born to infected women in a tertiary center in Poznan, Poland. (2) Methods: The study comprised 101 newborns delivered by women infected with SARS-CoV-2. The control group consisted of 101 newborns born before the pandemic. Data were collected retrospectively from the medical records. (3) Results: Most newborns of SARS-CoV-2-positive mothers were delivered by cesarean section—83.17% vs. 40.59% in the control group (p < 0.05). The groups did not differ in Apgar scores and the need for resuscitation. Newborns of SARS-CoV-2-positive mothers were more likely to present with respiratory distress and require respiratory support. The most common diagnosis was transient tachypnea of the newborn, not correlated with the mode of delivery. Newborns of the study group were never exclusively breastfed, 0% vs. 64.36% (p < 0.05). None of the patients in the study group was tested positive for the virus. (4) Conclusions: Infants born to SARS-CoV-2-positive mothers seem to be more at risk of moderate respiratory failure than other newborns. Separation of mother–baby dyads results in a dramatic fall in breastfeeding in the short-term post-partum period.

Highlights

In December 2019, a newly identified coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2) caused an outbreak of coronavirus disease (COVID-19)in Wuhan, in Hubei Province, China, and has since been spreading worldwide [1]
The groups did not differ in pregnancy complications such as hypertension, diabetes, or intrauterine infection; intrauterine growth restriction (IUGR) was observed significantly more frequently in the control group than in the COVID-19 group
Most newborns of SARS-CoV-2-positive mothers were delivered by cesarean section (83.17% vs. 40.59%, p < 0.05)

Summary

Introduction

In December 2019, a newly identified coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2) caused an outbreak of coronavirus disease (COVID-19)in Wuhan, in Hubei Province, China, and has since been spreading worldwide [1]. In December 2019, a newly identified coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2) caused an outbreak of coronavirus disease (COVID-19). On. 30 January 2020, the World Health Organization (WHO) declared the outbreak of COVID-19 as a Public Health Emergency of International Concern [2]. As we know, people of all ages are susceptible to SARS-CoV-2, while the elderly and those with underlying diseases are more fragile to the virus. Hundreds of pediatric cases have been documented, including neonatal infection. This situation has drawn the public’s attention to neonatal infection [3]. SARS-CoV-2 may spread from person to person by droplets from respiratory secretions

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