Clinical characteristics of heart failure with median ejection fraction

Abstract

Objective To investigate clinical characteristics of heart failure (HF) with median ejection fraction. Methods From January, 2015 to January, 2016, two hundred and nine patients with a discharge diagnosis of HF (NYHA II-IV) admitted into our hospital were collected. The patients were stratified by LVEF as preserved (HFpEF, LVEF≥50%, n=53) , median (HFmrEF, LVEF 40%-49%, n=46) , and reduced (HFrEF, LVEF<40%, n=110). The clinical data were compared. Results Compared with the HFpEF group, the HFmrEF group had more patients with coronary disease, higher hemoglobin, and lower left atrium diameter, as well as lower interventricular septal thickness and left ventricular posterior wall thickness (all P<0.05) . Compared with the HFrEF group, the patients in the HFmrEF group were older [ (71.28 10.81) vs. (63.81 13.38) ], and more patients had coronary disease, as well as higher systolic blood pressure (P<0.05) ; besides, their BNP level, mean platelet volume, purine trione , left atrium diameter, left ventricular anteroposterior diameter, and pulmonary arterial pressure were lower (all P<0.05) Conclusions HFmrEF only accounted for 22.01% of the patients with HF. The clinical characteristics of HFmrEF in this study suggested that being older and having coronary disease might play important roles. Key words: Heart failure; Ejection fraction; Clinical characteristics