Abstract

We report the clinical characteristics and management of fourteen neonates and very young infants with COVID-19. Although all presented with mild symptoms and did not require specific treatment, most of them had abnormal laboratory and radiological findings. Ten infants presented with neutropenia and/or monocytosis but none with lymphopenia. Transient hypertriglyceridemia and/or prolonged viral shedding were detected in 9 patients.Conclusion: Based to our experience, COVID-19 is mild in very young infants and might have distinct laboratory findings. What is Known:• SARS-CoV-2 in infants is a mild disease.• The period of transmission is approximately 2 weeks.What is New:• Very young age is not a risk factor for severe COVID-19 but could be associated with prolonged viral shedding.• Neutropenia and monocytosis are distinct characteristics of COVID-19 in very young infants.

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