Clinical Characteristics of Concomitant Primary Biliary Cirrhosis and Graves? Disease: A Literature Review

Abstract

Although, Hashimoto’s thyroiditis (HT) is commonly characterized by extrahepatic manifestation of PBC, the coexistence of primary biliary cirrhosis (PBC) and Graves’ disease (GD) is uncommon. Here, we conducted a review of the English and Japanese literature, including proceedings, regarding the coexistence of PBC and GD. Of 24 reviewed patients, all of who were female, there was no clear tendency of one disease to precede the other. Of two patient deaths, one was due to liver failure as a result of PBC progression.