Abstract
BackgroundThe outbreak of COVID-19 has rapidly spread to Italy, including Pesaro-Urbino province. Data on young to middle age adults with COVID-19 are lacking. We report the characteristics, management and health-related quality of life (HRQoL) in patients with COVID-19 aging ≤50 years.MethodsA retrospective analysis was performed in all patients ≤50 years with a confirmed diagnosis of COVID-19 admitted to Emergency department (ED) of San Salvatore Hospital in Pesaro from February 28th to April 8th, 2020. Data were collected from electronical medical records. HRQoL was investigated after 1 month from hospital discharge using the SF-36 questionnaire. Outcomes were evaluated between hospitalized and not hospitalized patients.ResultsAmong 673 patients admitted to the ED and diagnosed with COVID-19, 104 (15%) were ≤ 50 years old: 74% were discharged at home within 48 h, 26% were hospitalized. Fever occurred in 90% of the cases followed by cough (56%) and dyspnoea (34%). The most frequent coexisting conditions were hypertension (11%), thyroid dysfunction (8%) and neurological and/or mental disorders [NMDs] (6%). Mean BMI was 27. Hypokalaemia and NMDs were significantly more common in patients who underwent mechanical ventilation. Regardless of hospitalization, there was an impairment in both the physical and mental functioning.ConclusionsOverweight and hypertension are frequent conditions in young to middle age adults with COVID-19. Hypokalaemia and NMDs are commonly associated with progressive disease. A significant impact on HRQoL in the early stage of post-discharge is common in this population.
Highlights
The outbreak of COVID-19 has rapidly spread to Italy, including Pesaro-Urbino province
Patients A retrospective analysis was performed on the confirmed cases of COVID-19, who were admitted to Emergency department (ED) of San Salvatore Hospital in Pesaro from February 28th to April 8th, 2020
Hypertension was the most frequent coexisting condition being observed in 11% of the patients, followed by thyroid dysfunction (8%), and neurological and/or mental disorders (6%)
Summary
The outbreak of COVID-19 has rapidly spread to Italy, including Pesaro-Urbino province. Data on young to middle age adults with COVID-19 are lacking. Management and healthrelated quality of life (HRQoL) in patients with COVID-19 aging ≤50 years. Methods: A retrospective analysis was performed in all patients ≤50 years with a confirmed diagnosis of COVID-19 admitted to Emergency department (ED) of San Salvatore Hospital in Pesaro from February 28th to April 8th, 2020. In early December 2019, 41 cases of coronavirus disease 2019 (COVID-19) were described in Wuhan in Hubei Province [1]. The outbreak of the new pandemic coronavirus pneumonia has rapidly spread all over the world, included Europe and Italy, with an increasing number of cases. The median age of the Italian patients was 62 years old; patients between 19 and 50 years old represented the 28% of the infected population, while patients older than 50 were the 70% [4]
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