Clinical Characteristics and Report of Seven Iranian Neonates Born to Mothers with Covid-19

Farhad Abolhasan Choobdar,Ezzat Abbariki,Maral Ghassemzadeh,Mohammad Attarian

doi:10.11648/j.ajp.20200603.32

Abstract

The outbreak of Covid-19 infection is an actual public health challenge. Iran is fighting hard against the virus outbreak. Although at first it seemed that the disease does not affect infants and the neonates, But the population of affected infants and neonates appears to be increasing. This article is written to share some of the experiences about encountering with neonates born to mothers with covid-19. It describes the maternal, perinatal and neonatal aspects of the disease in seven Iranian cases. It also explains the outcome of delivery and follow up of mothers and their neonates after they discharged from hospital. According to our vague and incomplete knowledge about this novel disease and also hazardous side effects of its specific drugs which are not fully evaluated in neonatal population, in this article we just emphasize on routine and supportive care and avoiding unconventional therapy. In this case series we manage our patients according to their disease such as pneumonia, transient tachypnea of neonates or respiratory distress syndrome by using antibiotics, total parenteral nutrition and supplementary oxygen therapy with the preference of non-invasive methods. We didn’t use any novel treatment for Covid-19 disease. We also carefully considered isolation and personal protection issues.

Highlights

Results from initial investigation showed that most of the infected patients had been exposed at the Hunan wholesale seafood market and from that point pneumonia caused by novel sever acute respiratory syndrome (SARS-Cov2) appeared in Wuhan
All the neonates who born to infected mothers between February 20 and May 21, 2020 and who were admitted in NICU wards at two hospitals which are Iran University of medical sciences subset (Firuzgar and Lolagar hospitals) were included in this study
The diagnosis of mothers was initially begun according to clinical symptoms, These clinical presentations should be confirmed by high resolution CT scan evidence of typical viral pneumonia that is bilateral and peripheral ground-glass and consolidative pulmonary opacities

Summary

Introduction

In December 2015 Menachery et al published an article in which they inspirationally predicted the future treat of Sever acute respiratory syndrome coronavirus (SARS-CoV). They mentioned that this virus was circulating in Chinese horseshoe bat population in that time [1]. Results from initial investigation showed that most of the infected patients had been exposed at the Hunan wholesale seafood market and from that point pneumonia caused by novel sever acute respiratory syndrome (SARS-Cov2) appeared in Wuhan. The outbreak was reported by china to WHO on December 31 and WHO announced a pandemic state of coronavirus disease2019 (covid19), caused by SARS-Cov2 [4]

Methods

Discussion

Conclusion