Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19

Abstract

AimsTo define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA). Materials and methodsWe performed a single-center retrospective study of IHCA cases. Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year. Return of spontaneous circulation (ROSC), 30-day survival, and cerebral performance category (CPC) at 30-days were assessed. ResultsFifty-five patients with COVID-19 suffering IHCA were identified and compared to 55 consecutive IHCA patients in 2019. The COVID-19 cohort was more likely to require vasoactive agents (67.3% v 32.7%, p=0.001), invasive mechanical ventilation (76.4% v 23.6%, p<0.001), renal replacement therapy (18.2% v 3.6%, p=0.029) and intensive care unit care (83.6% v 50.9%, p=0.001) prior to IHCA. Patients with COVID-19 had shorter CPR duration (10min v 22min, p=0.002). ROSC (38.2% v 49.1%, p=0.336) and 30-day survival (20% v 32.7%, p=0.194) did not differ. A 30-day cerebral performance category of 1 or 2 was more common among non-COVID patients (27.3% v 9.1%, p=0.048). ConclusionsReturn of spontaneous circulation and 30-day survival were similar between IHCA patients with and without COVID-19. Compared to previously published data, we report greater ROSC and 30-day survival after IHCA in COVID-19.