Clinical characteristics and mid-term outcome of patients with slow coronary fl ow

Abstract

Objective Due to uncertainty in the clinical implications of slow coronary fl ow (SCF), we aimed to investigate the clinical features and mid-term outcome of the Iranian patients with the slow coronary fl ow phenomenon.Methods During a four-year period from January 2005 to December 2009, out of 3523 consecutive patients who underwent coronary angiography in the Tehran Heart Center, 325 patients with no stenosis, ectasia, or aneurysm were enrolled in the study. Among them 81 (2.2%) patients were diagnosed with SCF. Baseline characteristics, lab parameters, coronary risk factors and mid-term outcome were described, consequently.Results Typical chest pain was the most frequent complaint in both groups (normal fl ow; 118 (48.4%) vs slow fl ow; 45 (55.6%)). RCA was the most frequently involved vessel for coronary slow fl ow followed by LCX and LAD and the combination of LCX and LAD involvement for coronary slow fl ow accounts for 27.2% of cases and three vessel involvement counts for 23.5%. Most patients experienced no symptoms during the follow-up period (Nl; 66.4% vs slow fl ow; 59.3%). However, three patients (3.7%) in the SCF group who underwent a second angiography 2-4 years later, were redefi ned as slow coronary fl ow.Conclusions We could not show any signifi cant diff erence with respect to initial presentation, coronary risk factors and even mid-term outcome of these patients in comparison to the normal group. However, due to the persistence of the SCF phenomenon even after 2-4 years in the second angiography of our three patients, it seems that slow fl ow might be a permanent rather than a transient manifestation.