Clinical characteristics and dynamic evaluation of hematoma morphology in patients with aspirin-related intracerebral hemorrhage.

Abstract

With the increasing awareness of thrombotic disease prevention and treatment, as well as advancements in cardiac valve replacement and cardiovascular disease resection surgeries, patients undergoing these procedures require antithrombotic medications. This work aimed to explore the dynamic changes in hematoma morphology and volume in aspirin-related intracerebral hemorrhage (ARICH). 43 cases with ARICH were selected as the experimental group and 40 cases of non-antithrombotic drug-related cerebral hemorrhage (non-ATT-ICH) were enrolled in the control group. General information about the two study groups was collected, and the initial laboratory test indices upon admission for each patient were recorded. Hematoma volumes were recorded within 6 hours, 24±3 hours, 72 hours, and 7 days after the onset of the disease. Volume changes were observed, and the absorption rates of the hematoma at 1 day, 3 days, and 7 days after onset were calculated. In the baseline data, the baseline hematoma volume of the experimental group (19.37±3.21) was slightly higher than that of the control group (15.73±2.78), showing a statistically significant difference (p<0.05). In terms of hematoma morphology and location, the hematoma morphology irregularity of the experimental group compared with the control group was 67% vs. 40%. In terms of hematoma growth and expansion, patients with ARICH had a larger volume of hematoma growth within 1 to 3 days of onset. At 3 d and 7 d, the experimental group's absorption rate was higher than the control group, and the experimental group's hematoma absorption rate was faster than the control group. The experimental group's hematoma morphology was mostly irregular, as can be seen (67%). If the hematoma volume increased from 1 d to 3 d after the onset of the disease, the hematoma volume of the patients in the experimental group was larger. The hematoma absorption rate of the experimental group was faster than that of the control group from 72 h to 7 d. The morphology of ARICH hematoma was mainly irregular (67%). In ARICH patients, if the hematoma volume rose within 1-3 days of initiation, the hematoma volume increased even more. Compared with non-ATT-ICH, ARICH had a faster rate of hematoma absorption at 3-7 d.