Abstract
Background: This study aims to evaluate the clinical characteristics, complications, degree of glycemic control, and cardiovascular risk factor control in patients with type 1 diabetes in Catalonia (Northwest of Spain). Methods: Cross-sectional study using a database including clinical, laboratory, and treatment data. Patients with an ICD10 diagnosis of type 1 diabetes were included, excluding those treated with glucose-lowering agents other than insulin, or treated only with basal insulin two years after diagnosis. Results: 15,008 patients were analysed. Median IQR age was 42 (31–53) years, diabetes duration 11.8 (6.8–16.0) years, 56.5% men. Median (IQR) HbA1c was 7.9% (7.1–8.8). Microvascular complications were present in 24.4% of patients, 43.6% in those with a diabetes duration >19 years. In presence of known cardiovascular disease 69.3% of patients showed an LDL-C concentration >70 mg/dL, 37% had a systolic blood pressure >135 mmHg and 22.4% were smokers. Conclusions: This study provides a reliable snapshot about the clinical situation of a large population of patients with T1D in Catalonia, which is similar to that of other western areas. The lack of adequate control of cardiovascular risk factors in a significant proportion of patients with cardiovascular disease deserves a more detailed analysis and urges the need for improvement strategies.
Highlights
Type 1 diabetes (T1D) is one of the most prevalent chronic diseases during childhood and youth
T1D accounts for a minor proportion of patients with diabetes globally, it is still a major health issue because it often affects young people who will live with the disease for many years, increasing the probabilities of microvascular and macrovascular complications [6,7]
We conducted a cross-sectional study including all patients with T1D registered with the Catalan Health Institute (CHI) of Catalonia, a Mediterranean region in north-eastern
Summary
Type 1 diabetes (T1D) is one of the most prevalent chronic diseases during childhood and youth. A better understanding of the clinical status and characteristics of individuals with T1D can help healthcare providers to develop strategies to improve patient care and to better adapt the management and treatment of the disease to internationally recognized standards of clinical practice [14]. With this in mind, this study sought to describe the clinical characteristics, burden of complications, degree of glycemic control, and cardiovascular risk factor control, as well as treatment in a large population-based cohort of patients with T1D in Spain.
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