Clinical characteristics analysis of 146 Han and the Uyghur cases with Behçet's disease in Xinjiang Uygur Autonomous region

Abstract

Objective To discuss the characteristics of in-patients with Behcet's disease in Xinjiang Uygur Autonomous region. Methods Clinical data of 146 cases with Behcet's disease admitted to Xinjiang Uygur Autonomous region people's hospital were analyzed. The demographic data and clinical manifestations were analyzed retrospectively. The categorical data was compared using χ2 test or Fisher's exact test. Results ① Of the 146 patients with BD, 99 cases were Han, 47 cases were uyghurs. Oral ulcer were observed in 146 cases (100%). Genital ulcer occurred in 115 cases (78.8%), of which 76 were Han (76.8%), 39 (82.9%) were uyghurs, the difference was not significant (P=0.391). The initial presentation was oral ulcer in 83 cases (56.8%), of which 60 cases (60.6%) were Han, 23 cases (48.9%) were the uyghurs. The second most common presentation was oral ulcer and genital ulcer, which occurred in 42 cases (28.8%), of which 23 cases (23.2%) were Han, 19 cases (40.4%) were the uyghurs. More Han patients initially presented with both oral and genital ulcers than uyghur (P=0.032). ② Skin lesions were recorded in 66 cases (45.2%), of which 45 cases (45.4%) were Han, 21 cases (44.7% ) were the uyghurs, the difference was not significant (P=0.930). ③ Joint damage occurred in 40 cases (27.4%), of which 22 cases (22.2%) were Han, 18 cases (38.3%) were the uyghurs. Joint damage wasmore frequently observed in Han than in uyghur (P=0.042). ④ Eye lesion happened in 21 cases (14.4%), ofwhich 9 cases (9.1%) were Han, 12 cases (25.5%) were the uyghurs, ie, eye lesion of Uyghur was higher than Han (P=0.008). ⑤ Vascular lesions were detected in 8 cases (5.5%), of which the 5 cases were Han, 3 cases were uyghurs, the difference was not significant (P=0.712). ⑥ Nervous lesions were observed in 2 cases (1.37%), 1 was Han and one was uyghur, the difference was not significant (P=0.542). Conclusion The most common clinical presentations of BD in Xinjiang region are oral and genitalulcers. Skin, joints, eye, vascular, nervous system can also be affected. Joint damage in Han is higher than Uyghur ,but eye lesion of Uyghur is more common than Han. Key words: Behcet syndrome; Han nationality; Uygur nationality