Clinical case of neonatal lupus with cartilaginous metaplasia, fibrosis and calcification of the atrioventricular node zone

Abstract

Neonatal lupus is a rare disease associated with the circulation in the mother’s blood of one or more autoantibodies to soluble intracellular ribonucleoproteins Ro/SS-A and La/SS-B. This disease is extremely often manifested by congenital heart block, which can progress even after the birth of a child. We have described a case of fibrosis, calcification and cartilaginous metaplasia of the atrioventricular node zone, which caused complete atrioventricular block in a child who died from neonatal lupus.