Abstract

The article describes in detail the clinical case of a severe course of a combined viral disease (Varicella-Zoster, Hantaan Hemorrhagic Fever), complicated by bilateral interstitial pneumonia, cerebral edema, and disseminated vascular coagulation syndrome, developed in an immunocompromised patient during the treatment period of exacerbation of a background disease (plaque psoriasis, progressive stage) with a cytostatic drug. The role of the main and associated diseases (pathogenetic mechanisms of comorbidity), specificly, hantavirus infection and psoriasis, as co-factors in the formation of an unfavourable course of varicella-zoster in an adult, is discussed. An example of an individual approach to the patient, a comprehensive diagnosis and rational treatment that contributed to a favorable outcome of the disease is given.

Highlights

  • The article describes in detail the clinical case of a severe course

  • rational treatment that contributed to a favorable outcome of the disease is given

  • Поражение легких при геморрагической лихорадке с почечным синдромом (клиническое наблюдение) [Текст] / Д

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Summary

Introduction

The article describes in detail the clinical case of a severe course of a combined viral disease (Varicella-Zoster, Hantaan Hemorrhagic Fever), complicated by bilateral interstitial pneumonia, cerebral edema, and disseminated vascular coagulation syndrome, developed in an immunocompromised patient during the treatment period of exacerbation of a background disease (plaque psoriasis, progressive stage) with a cytostatic drug. С диагнозом ветряная оспа (источник инфекции неизвестен) пациент был переведен в инфекционное отделение, где в течение 5 дней отмечались обильные высыпания на коже и слизистых, прогрессирующие явления интоксикации, фебрильная лихорадка.

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