CLINICAL BENEFITS OF CULTURING INTRACYTOPLASMIC SPERM INJECTION-DERIVED NONPRONUCLEATED (0PN) AND MONOPRONUCLEATED (1PN) ZYGOTES, AND THE IMPORTANCE OF VERIFYING BIPARENTAL CHROMOSOME INHERITANCE IN 1PN-DERIVED BLASTOCYSTS

Kathryn Wozniak,Amy Jones,Minjae Kwon,Ping Zou,Mitchel C Schiewe

doi:10.1016/j.fertnstert.2021.07.017

CLINICAL BENEFITS OF CULTURING INTRACYTOPLASMIC SPERM INJECTION-DERIVED NONPRONUCLEATED (0PN) AND MONOPRONUCLEATED (1PN) ZYGOTES, AND THE IMPORTANCE OF VERIFYING BIPARENTAL CHROMOSOME INHERITANCE IN 1PN-DERIVED BLASTOCYSTS

Kathryn Wozniak, Amy Jones + Show 3 more

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https://doi.org/10.1016/j.fertnstert.2021.07.017

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Journal: Fertility and Sterility

Publication Date: Sep 1, 2021

Affiliation: Ovation Fertility

#Preimplantation Genetic Testing For Aneuploidy #1PN Zygotes + Show 8 more

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Abstract

Evaluate the developmental competence and aneuploidy status of blastocysts derived from 0PN and 1PN zygotes following intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing for aneuploidy (PGT-A). Elucidate biparental chromosome inheritance in female 1PN-derived blastocysts.

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