Abstract
Objective To study the impact of TNM staging (AJCC,7th edition,2010) and the modes of surgical treatment on the prognosis of patients with gallbladder cancer.Methods The data of 151 patients with primary carcinoma of the gallbladder (PCG) treated in our hospital from January 1998 to June 2013 were retrospectively analyzed.Results For patients with stage 0-Ⅰ PCG,survival after radical cholecystectomy was not significantly longer than that of simple cholecystectomy (x2 =0.820,P =0.365).However,in patients with stage Ⅱ,those treated by radical cholecystectomy had significantly better prognosis than those treated by simple cholecystectomy (x2 =4.151,P =0.042).The prognosis of the radical cholecystectomy group was superior to the palliative cholecystectomy group for both stage Ⅲ A (x2 =4.511,P =0.034) and stage ⅢB (x2 =4.389,P =0.036).While in stage Ⅳ A,the difference between the radical cholecystectomy group and the palliative cholecystectomy group (including other treatment) was not significant (x2 =0.163,P =0.686).Conclusions Simple cholecystectomy is a good surgical procedure for patients with stages 0 and Ⅰ PCG,while for patients with stages Ⅱ and Ⅲ PCG,radical cholecystectomy should be carried out.For stage Ⅳ PCG,palliative treatment or other conservative treatment may be a proper treatment. Key words: Gallbladder neoplasms ; TNM staging; Surgical procedures ; Prognosis
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