Abstract
Clinical Assessment of Anti-inflammatory Activity of 940 Nanometer Low Level laser Therapy on Carrageenan Induced Arthritis in Temporomandibular Joint in Wistar Albino Rats
Highlights
Temporomandibular joint disorders (TMDs) are considered as the most common nondental-related orofacial pain conditions which are usually presents with an inflammatory component 1,2 many types of non-surgical treatments are usually used to treat TMDs to improve and enhance function and to reduce or cure symptoms 3such as physical therapy[4 ], drug therapy[2,5], various types of occlusal splints4,6, acupuncture[7] and low level laser therapy[3] which is very promising method to treat TMDs2,3,8
The aim of this study was to evaluate the possible anti-inflammatory effect of 940nm diode laser in treating carrageenan induced arthritis in temporomandibular joint in Wistar albino rats, using different energy density of level laser therapy (LLLT), by clinical assessment of the inflammation. it was concluded that 74J/cm[2] LLLT had very efficient in edema reduction and restore function with good anti-inflammatory effect, on the other hand 171J/cm[2] had appear to be in or near the borderline between non-thermal and thermal lasers eradiation in considering to Westar rat skin
Carrageenan is an extract of seaweeds; Chondrus spp. and Gigartinaspp which is commonly known as Irish moss, chemically it is a sulphatedmucopolysaccharide[9], for many years it had been used to induce inflammation in rat joints as in footpad, paw[10] and temporomandibular joint[2,5], carrageenan induced arthritis is the most common and reliable method to test new anti-inflammatory drugs effectiveness and assessment of new strategies to treat inflammatory arthritis[2,11]
Summary
Temporomandibular joint disorders (TMDs) are considered as the most common nondental-related orofacial pain conditions which are usually presents with an inflammatory component 1,2 many types of non-surgical treatments are usually used to treat TMDs to improve and enhance function and to reduce or cure symptoms 3such as physical therapy[4 ], drug therapy[2,5], various types of occlusal splints4,6 , acupuncture[7] and low level laser therapy[3] which is very promising method to treat TMDs2,3,8. The aim of this study was to evaluate the possible anti-inflammatory effect of 940nm diode laser in treating carrageenan induced arthritis in temporomandibular joint in Wistar albino rats, using different energy density of LLLT, by clinical assessment of the inflammation.
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