Abstract
The presence of combined pathology is an aggravating factor for the course of COPD. The aim of the research: to assess the impact of GERD on the course of chronic obstructive pulmonary disease. As a result of a retrospective study of 102 patients who were hospitalized for exacerbations of COPD, it was found that the presence of GERD is associated with more frequent exacerbations of the disease, severe bronchial obstruction, which in turn leads to an increase in hospitalizations in this category of patients.
Highlights
The presence of concomitant gastroesophageal reflux disease (GERD) in patients with chronic obstructive pulmonary disease (COPD) is quite common in clinical practice today and is usually one of the reasons for the increase in respiratory symptoms [1,2,3]
If the occurrence of concomitant GERD is not diagnosed in time and is ignored its role in the impact on respiratory pathology and all of this is regarded as progression of COPD, increasing the treatment of the underlying disease by increasing doses of drugs, inhaled glucocorticosteroids, which in turn reduce in the tone of LES, creating additional favorable conditions for the formation of concomitant GERD [8] many questions related to the occurrence of concomitant GERD in patients with COPD, and with its timely diagnosis, do not have an unambiguous answers and often remain out of the attention of doctors and require further research
There are no statistically significant differences were found in patients with a combination of COPD and GERD (p> 0.005) during comparing groups by sex, age, smoking status, Patients with concomitant GERD compared with patients without GERD had a higher frequency of exacerbations of COPD (2.1 ± 0.3 and 1.8 ± 0.6, respectively, p
Summary
The presence of concomitant gastroesophageal reflux disease (GERD) in patients with chronic obstructive pulmonary disease (COPD) is quite common in clinical practice today and is usually one of the reasons for the increase in respiratory symptoms [1,2,3]. This pathological relationship, is due, on the one hand, that bronchial obstruction with GERD may be exacerbated by microaspiration of gastric contents into the trachea and bronchi, as well as during stimulation by n.vagus of the receptors of the distal part esophagus Materials and methods of the research: a retrospective analysis of 102 patients who were treated in the pulmonology department CNE “Transcarpathian regional clinical hospital named after Andriy Novak.
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