Clinical approach for periocular lymphoma

Abstract

Lymphomas occur very frequently in the periocular region, predominantly in adulthood. This malignant tumor shows aheterogeneous clinical pattern. The aim of this article is to provide an overview of the symptoms, diagnostic procedures and treatment options for lymphomas of the periocular region. The symptoms of periocular lymphomas are mostly nonspecific. The growth is usually painless and slowly progressive. Asalmon-colored swelling is typical for conjunctival lymphoma. The basis of aprecise diagnostic process is adetailed anamnesis. Contrast-enhanced magnetic resonance imaging (MRI) is considered the gold standard for imaging of lymphoproliferative lesions. A histopathological examination should be carried out to confirm the exact diagnosis. Subsequently, staging should be performed as periocular lymphomas can be the manifestation of a systemic involvement. The treatment procedure should be coordinated by an interdisciplinary tumor board. The treatment of periocular lymphomas can include percutaneous stereotactic irradiation as well as chemotherapeutic or new immunotherapeutic strategies.