Abstract
In this issue of Chest (see page 310) Takahashi and colleagues measured soluble interleukin-2 receptors in patients with lung disease and in healthy volunteers. They found higher levels in those with tuberculosis and sarcoidosis. The serum levels correlated with disease activity. This follows reports of increased soluble interleukin-2 receptors in serum and bronchoalveolar lavage fluid in patients with sarcoidosis,1,2 and is one of several recent articles that indicate how knowledge of T-cell proteins and their receptors may be applied clinically in the future.
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