Clinical application of transcutaneous partial oxygen tension detection in the hyperbaric chamber

Abstract

Objective To observe the effects of different oxygen-breathing modes on transcutaneous partial oxygen tension (TcPO2) in the hyperbaric chamber.Methods Changes in TcPO2 of the patients were detected with the QSG-1000B multiple function monitor in the course of HBO treatment.Results TcPO2 level elevated with the extension of HBO treatment and reached peak (1 214 mmHg) at minute 45.For the patients in the oxygen mask-breathing group,TcPO2 level reached 1 214 ± 134 mmHg at minute 45,and very significant differences could be noted,when it was compared with that detected at minute 15 (P ＜ 0.01).For the patients in the oxygen hood-breathing group (with airway incision),TcPO2 level reached as high as (1 304 ± 269) mmHg at minute 45,and very significant differences could also be noted,when it was compared with that detected at minute 15 (P ＜ 0.01).For the patients in the oxygen hood-breathing group (without airway incision),TcPO2 level reached as high as (1 382 ± 80) mmHg at minute 45,and very significant differences could also be noted,when it was compared with that detected at minute 15 (P ＜ 0.01).However,no significant differences in TcPO2 levels at minute 45 could be noted,when comparisons were made between the 3 groups (P ＞ 0.05).The patients had air-breathing interval of 5 min,and TcPO2 level detected at minute 55 was relatively lower,then TcPO2 level elevated gradually at minute 65 and 75.There were no statistical significance in TcPO2 levels detected at all the time points (P ＞ 0.05).Conclusions TcPO2 detection in the hyperbaric chamber was of great significance to clinical physicians in understanding the efficacy of HBO therapy.It was recommended that TcPO2 index be used as a routine detection method. Key words: Transcutaneous partial oxygen tension; Hyperbaric chamber; Hyperbaric oxygen