Abstract
Objective To explore the clinical efficacy and safety of on-line hemodiafiltration (online-HDF) in treatment of chronic renal failure.Methods 82 patients with chronic renal failure who had been treated in our hospital were randomly assigned to HD group (38 patients) and HDF/HD group (44 patients).HD group underwent conventional hemodialysis,while HDF/HD group received hemodialysis twice and then hemodiafiltration.The changes in blood levels of Cr,BUN,and phosphorus and the complications were compared between the two groups after treatment.Results There were no statistical differences in levels of Cr and BUN in HDF/HD group after treatment; whereas serum phosphorus level differed significantly between HDF/HD group and HD group (P＜0.05).The incidence rate of complications was lower in HDF/HD group than in HD group.Conclusions On-line hemodiafiltration is safe and convenient and has remarkable efficacy in the treatment of chronic renal failure. Key words: Chronic renal failure; On-line hemodiafiltration; Hemodialysis
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