Clinical application of fecal occult blood testing of hemoglobin and transferrin at the same time

Abstract

Objective To discuss the clinical value when using o-aniline, colloidal gold detection paper hemoglobin (Hb),transferrin colloidal gold detection paper (Tf) at the same time for fecal occult blood test to diagnose diseases of the gastrointestinal disease bleeding. Methods On 100 cases of healthy people specimens, with o-aniline, hemoglobin of colloidal gold paper, transferrin colloidal gold diagnostic test paper fecal occult blood test. Results Of 100 healthy people o-aniline positive rate of 12%, hemoglobin positive rate of 2.0%,transferrin positive rate of 2.0%, while the detection of hemoglobin and transferrin in the stool, positive rate is2.0%:152 cases of the disease have gastrointestinal bleeding in patients with o-toluidine positive rate of 69.5%,hemoglobin positive rates of 73.0%, transferrin positive rate of 88.2 %, while the detection of hemoglobin and transferrin in the stool, positive rate is 91.2%. Conclusions Immunity assay has high sensitivity and specificity. But hemoglobin due to the role of intestinal bacteria and the intestinal mucus composition of the infection and then cause variability, it can cause a false negative response. So use hemoglobin and transferring to mensurate gastrointestinal bleeding at the same time may increase the positive rate. Key words: Fecal occult blood; Transferrin; Hemoglobin; O-aniline